Linked Life Data

9279411

Source:http://linkedlifedata.com/resource/pubmed/id/9279411

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-9-30
pubmed:abstractText
An adult female canebrake rattlesnake (Crotalus horridus atricaudatus) at Zoo Atlanta (Atlanta, Georgia, USA) had a subcutaneous mass on the left lateral abdomen. Microscopically, the tumor contained a pleomorphic population of cells with abundant intracytoplasmic brown to gold nonrefractile pigment (chromatophores), large stellate cells resembling neurons, and small stellate cells whose cytoplasmic processes formed a fibrillar matrix. The pigment stained black with the Fontana-Masson technique and was positive with the periodic acid-Schiff technique (prior to and after diastase treatment). Neuron-specific enolase was detected in the large stellate cells using an immunohistochemical staining technique. In addition, glial fibrillary acidic and S-100 proteins were detected in the chromatophores with immunohistochemical staining. The smaller stellate cells were strongly S-100 positive. Ultrastructurally, chromatophores contained intracytoplasmic structures composed of concentric lamellar membranes bordered by a triple-layer outer membrane. The morphology of these structures was compatible with pterinosomes. Three fluorescent pigments were isolated from the neoplasm by one-dimensional chromatography and characterized by spectrophotometry and spectrofluorometry.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1042-7260
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
198-203
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Malignant chromatophoroma in a canebrake rattlesnake (Crotalus horridus atricaudatus).
pubmed:affiliation
Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens 30602, USA.
pubmed:publicationType
Journal Article, Case Reports