rdf:type |
|
lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-9-17
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pubmed:databankReference |
|
pubmed:abstractText |
We have purified and partially sequenced a protein from the adventitia of the human aorta (aortic aneurysm antigenic protein 40 kDa; AAAP-40) that has homologies to bovine aortic microfibril-associated glycoprotein (MAGP-36). It is immunoreactive with immunoglobulin G (IgGs) purified from the serum and aortic wall of patients with abdominal aortic aneurysms. AAAP-40 and MAGP-36 have fibrinogen-like and vitronectin-like motifs. Screening an expression library constructed from human aortic adventitial messenger RNA has resulted in the cloning of three complementary DNAs whose gene products are immunoreactive with immunoglobulin G from patients with abdominal aortic aneurysms. Two strongly resemble each other and have been described separately. The purpose of this article is to report the third clone.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0741-5214
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
26
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
313-8
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9279320-Amino Acid Sequence,
pubmed-meshheading:9279320-Aortic Aneurysm, Abdominal,
pubmed-meshheading:9279320-Cloning, Molecular,
pubmed-meshheading:9279320-Contractile Proteins,
pubmed-meshheading:9279320-DNA, Complementary,
pubmed-meshheading:9279320-Elastic Tissue,
pubmed-meshheading:9279320-Extracellular Matrix Proteins,
pubmed-meshheading:9279320-Gene Expression Regulation,
pubmed-meshheading:9279320-Humans,
pubmed-meshheading:9279320-Immunoglobulin G,
pubmed-meshheading:9279320-Molecular Sequence Data,
pubmed-meshheading:9279320-RNA, Messenger,
pubmed-meshheading:9279320-Sequence Alignment,
pubmed-meshheading:9279320-Sequence Homology, Nucleic Acid,
pubmed-meshheading:9279320-Transcription, Genetic
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pubmed:year |
1997
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pubmed:articleTitle |
Molecular cloning of the complementary DNA for an additional member of the family of aortic aneurysm antigenic proteins.
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pubmed:affiliation |
Columbia University, New York, NY, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|