Linked Life Data

9275622

Source:http://linkedlifedata.com/resource/pubmed/id/9275622

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-9-9
pubmed:abstractText
In order to explore the change of urinary excretion of platelet activating factor (PAF) and its significance in patients with primary nephrotic syndrome (PNS), we determined the urinary and plasma PAF in 12 cases of PNS, using platelet aggregation bioassay. The results showed that the level of urinary PAF was significantly higher in patients with PNS (n = 12) than in healthy controls (n = 10), but that of plasma PAF was comparable in patients with PNS and controls, suggesting that the excessive generation of PAF is confined to kidney. There was a significant positive correlation between urinary excretion of PAF and proteinuria (r = 0.73, P < 0.01). The results indicated that increased urinary excretion of PAF can serve as an indicator for augmentation of the permeability of glomerular basement membrane (GBM) in PNS.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0578-1426
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
83-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
[Changes in urinary excretion of platelet activating factor and its significance in patients with primary nephrotic syndrome].
pubmed:affiliation
Department of Nephrology, Second Affiliated Hospital, Guangzhou Medical College.
pubmed:publicationType
Journal Article, English Abstract