Linked Life Data

9275289

Source:http://linkedlifedata.com/resource/pubmed/id/9275289

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1997-9-18
pubmed:abstractText
The action of cysteinesulfinate, the substrate of the aspartate/glutamate antiporter on the palmitate-induced uncoupling in rat liver mitochondria and the recoupling effect of glutamate, aspartate, and diethyl pyrocarbonate was studied. In the presence of palmitate and an inhibitor of the ADP/ATP-antiporter carboxyatractylate, cysteinesulfinate exerted a relatively week recoupling effect. However, it significantly decreased the recoupling action of glutamate, aspartate, and diethyl pyrocarbonate. In the presence of cysteinesulfinate, these compounds caused recoupling at higher concentrations. The data show that the recoupling action of glutamate, aspartate, and diethyl pyrocarbonate is due to their interaction with the aspartate/glutamate antiporter. The data also confirm the suggestion that this anion carrier is involved in the uncoupling action of fatty acids.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-2979
pubmed:author
pubmed:issnType
Print
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
495-500
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Effect of cysteinesulfinate on fatty acid-dependent uncoupling: modulation of recoupling by substrates of the aspartate/glutamate antiporter and diethyl pyrocarbonate.
pubmed:affiliation
Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't