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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1997-9-10
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pubmed:abstractText |
Chloroquinoxaline sulfonamide (CQS) was one of the first agents identified by the human tumor colony-forming assay (HTCFA) as possessing antitumor activity in non-small-cell lung cancer (NSCLC). Prior phase I studies had suggested that plasma concentrations equivalent to those showing efficacy in the HTCFA could be reliably attained in humans. This phase II study assessed the antitumor activity of CQS while using an adaptive control pharmacokinetic modelling system to attain targeted plasma levels of this novel compound.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0344-5704
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
415-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9272118-Adult,
pubmed-meshheading:9272118-Aged,
pubmed-meshheading:9272118-Antineoplastic Agents,
pubmed-meshheading:9272118-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:9272118-Female,
pubmed-meshheading:9272118-Humans,
pubmed-meshheading:9272118-Lung Neoplasms,
pubmed-meshheading:9272118-Male,
pubmed-meshheading:9272118-Middle Aged,
pubmed-meshheading:9272118-Neoplasm Staging,
pubmed-meshheading:9272118-Quinoxalines,
pubmed-meshheading:9272118-Sulfanilamides,
pubmed-meshheading:9272118-Treatment Failure,
pubmed-meshheading:9272118-Tumor Stem Cell Assay
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pubmed:year |
1997
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pubmed:articleTitle |
Phase II trial of chloroquinoxaline sulfonamide (CQS) in patients with stage III and IV non-small-cell lung cancer.
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pubmed:affiliation |
Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. millerv@mskcc.org
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II
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