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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2-3
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pubmed:dateCreated |
1997-9-23
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pubmed:databankReference |
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pubmed:abstractText |
We report here the identification of the novel subunit of the mitochondrial F1F0-ATPase from Saccharomyces cerevisiae, ATPase subunit e. Yeast ATPase subunit e displays significant similarities in both amino acid sequence, properties (hydropathy and predicted coiled-coil structure) and orientation in the inner membrane, with previously identified mammalian ATPase subunit e proteins. Estimation of its native molecular mass and ability to be co-immunoprecipitated with a subunit of the F1-ATPase, demonstrate that subunit e is a subunit of the F1F0-ATPase. Stable expression of subunit e requires the presence of the mitochondrially encoded subunits of the F0-ATPase. Subunit e had been previously identified as Tim11 and was proposed to be involved in the process of sorting of proteins to the mitochondrial inner membrane.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0014-5793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
411
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-200
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pubmed:dateRevised |
2009-7-10
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pubmed:meshHeading |
pubmed-meshheading:9271204-Amino Acid Sequence,
pubmed-meshheading:9271204-Blotting, Western,
pubmed-meshheading:9271204-Carrier Proteins,
pubmed-meshheading:9271204-Chromatography, Gel,
pubmed-meshheading:9271204-Chromosomes, Fungal,
pubmed-meshheading:9271204-Cloning, Molecular,
pubmed-meshheading:9271204-Down-Regulation,
pubmed-meshheading:9271204-Fungal Proteins,
pubmed-meshheading:9271204-Gene Expression Regulation, Fungal,
pubmed-meshheading:9271204-Membrane Proteins,
pubmed-meshheading:9271204-Mitochondria,
pubmed-meshheading:9271204-Mitochondrial Proton-Translocating ATPases,
pubmed-meshheading:9271204-Molecular Sequence Data,
pubmed-meshheading:9271204-Precipitin Tests,
pubmed-meshheading:9271204-Promoter Regions, Genetic,
pubmed-meshheading:9271204-Protein Conformation,
pubmed-meshheading:9271204-Proton-Translocating ATPases,
pubmed-meshheading:9271204-Saccharomyces cerevisiae,
pubmed-meshheading:9271204-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:9271204-Sequence Analysis,
pubmed-meshheading:9271204-Sequence Homology, Amino Acid
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pubmed:year |
1997
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pubmed:articleTitle |
Yeast mitochondrial F1F0-ATPase: the novel subunit e is identical to Tim11.
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pubmed:affiliation |
Institut für Physiologische Chemie der Universität München, Munich, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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