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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1997-10-3
|
| pubmed:abstractText |
In the context of a study in Athens comprising 692 cases and 1,261 controls, we have evaluated the effect on breast cancer risk of the joint action of first-degree relative family history and established adult life risk factors. We created a risk score by assigning the value of 1 to women at high risk with respect to any of these risk factors and 0 otherwise, and summing these values, using weights equal to the excess odds ratio. The odds ratio for a tertile increment in the risk score was 1.5 [95% confidence interval (CI) = 1.3-1.8] among women without family history, and 2.3 (95% CI = 1.1-5.1) for women with family history. Our findings imply that women with a family history of breast cancer may benefit disproportionately by reduced exposure to adult life risk factors.
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
1044-3983
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
592-5
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9270964-Adult,
pubmed-meshheading:9270964-Age Factors,
pubmed-meshheading:9270964-Alcohol Drinking,
pubmed-meshheading:9270964-Breast Neoplasms,
pubmed-meshheading:9270964-Case-Control Studies,
pubmed-meshheading:9270964-Causality,
pubmed-meshheading:9270964-Cocarcinogenesis,
pubmed-meshheading:9270964-Environmental Exposure,
pubmed-meshheading:9270964-Female,
pubmed-meshheading:9270964-Greece,
pubmed-meshheading:9270964-Humans,
pubmed-meshheading:9270964-Logistic Models,
pubmed-meshheading:9270964-Middle Aged,
pubmed-meshheading:9270964-Obesity,
pubmed-meshheading:9270964-Odds Ratio,
pubmed-meshheading:9270964-Questionnaires,
pubmed-meshheading:9270964-Reproduction,
pubmed-meshheading:9270964-Risk Assessment,
pubmed-meshheading:9270964-Urban Health
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Evidence that adult life risk factors influence the expression of familial propensity to breast cancer.
|
| pubmed:affiliation |
Department of Hygiene and Epidemiology, University of Athens Medical School, Goudi, Greece.
|
| pubmed:publicationType |
Journal Article
|