Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1997-9-18
pubmed:abstractText
Specimens of antral mucosa were taken from five healthy volunteers and processed for microscopic evaluation. Consecutive 50-micron-thick sections were cut to estimate the volume of two antral glands. Two glands in each section were followed throughout by projecting their profiles from two microscopes mounted in parallel. The glandular volume was estimated using Cavalieri's principle. The mean volume of epithelial cells was estimated by systematic random sampling of the sections with an optical disector of known sample volume. The total number of cells per gland was calculated after determination of the volume of the glands and the mean volume of the epithelial cells. The mean volume of the antral glands was 13.6 +/- 1.67.10(6) microns3, whilst the mean volume of the epithelial cells was 1256 +/- 240 microns3. The total number of epithelial cells per gland was 11216 +/- 1104. In conclusion, using stereological methods, the total number of cells as well as the cell volume and the volume of antral glands can be determined in routine biopsy specimens of human stomach provided that the total depth of the mucosa is present in the section.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0903-4641
pubmed:author
pubmed:issnType
Print
pubmed:volume
105
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
571-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Three-dimensional estimation of the glandular volume, and of the number and volume of epithelial cells in two glands from the antral mucosa of five healthy volunteers.
pubmed:affiliation
Department of Medicine, Karolinska Institute, Danderyd Hospital, Stockholm, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't