Linked Life Data

9268791

Source:http://linkedlifedata.com/resource/pubmed/id/9268791

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1997-10-8
pubmed:abstractText
Postoperative drain blood was collected and reinfused using the ConstaVac system (Stryker, Kalamazoo, MI) in 30 patients after total knee arthroplasty. Of the total 1.1-L volume of postoperative bleeding, 60% was reinfused. No clinical complications were observed. Differences between venous blood and drain blood and between venous blood and drain blood after separate incubation were studied with respect to acidic and inflammatory effects on blood cells, plasma chemistry, and whole blood rheology. In drain blood, leukocyte and platelet counts were reduced (P < .001), probably as a result of consumption in the wound. Acidic incubation occurs in the drain container because of production of lactate from glucose, with a minimum pH at 5 hours of 7.2. The low pH caused slight but significant erythrocyte swelling (P < .01). The complement C3d indicated leukocyte activation, although of modest magnitude. Despite incubation and complement activation, maximum erythrocyte hemolysis after 24 hours of incubation was less than 1%. Drain blood showed a lower resistance against micropore filtration than venous blood (P < .001), mainly because of the reduced number of leukocytes, and remained unchanged with incubation. Although the autotransfusion system can be improved with respect to blood quality, filtered drain blood should be considered acceptable for reinfusion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0883-5403
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
517-25
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Autotransfusion after total knee arthroplasty. Effects on blood cells, plasma chemistry, and whole blood rheology.
pubmed:affiliation
Department of Orthopedics, University of Umeå, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't