| pubmed-article:9267021 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9267021 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:9267021 | lifeskim:mentions | umls-concept:C0291573 | lld:lifeskim |
| pubmed-article:9267021 | lifeskim:mentions | umls-concept:C0664613 | lld:lifeskim |
| pubmed-article:9267021 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:9267021 | lifeskim:mentions | umls-concept:C0010798 | lld:lifeskim |
| pubmed-article:9267021 | lifeskim:mentions | umls-concept:C1332098 | lld:lifeskim |
| pubmed-article:9267021 | lifeskim:mentions | umls-concept:C1413133 | lld:lifeskim |
| pubmed-article:9267021 | lifeskim:mentions | umls-concept:C0162610 | lld:lifeskim |
| pubmed-article:9267021 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:9267021 | lifeskim:mentions | umls-concept:C1334043 | lld:lifeskim |
| pubmed-article:9267021 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:9267021 | pubmed:dateCreated | 1997-9-8 | lld:pubmed |
| pubmed-article:9267021 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:abstractText | We report here the purification and cDNA cloning of Apaf-1, a novel 130 kd protein from HeLa cell cytosol that participates in the cytochrome c-dependent activation of caspase-3. The NH2-terminal 85 amino acids of Apaf-1 show 21% identity and 53% similarity to the NH2-terminal prodomain of the Caenorhabditis elegans caspase, CED-3. This is followed by 320 amino acids that show 22% identity and 48% similarity to CED-4, a protein that is believed to initiate apoptosis in C. elegans. The COOH-terminal region of Apaf-1 comprises multiple WD repeats, which are proposed to mediate protein-protein interactions. Cytochrome c binds to Apaf-1, an event that may trigger the activation of caspase-3, leading to apoptosis. | lld:pubmed |
| pubmed-article:9267021 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9267021 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9267021 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9267021 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:9267021 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:9267021 | pubmed:author | pubmed-author:LimPP | lld:pubmed |
| pubmed-article:9267021 | pubmed:author | pubmed-author:WangXX | lld:pubmed |
| pubmed-article:9267021 | pubmed:author | pubmed-author:HenzelW JWJ | lld:pubmed |
| pubmed-article:9267021 | pubmed:author | pubmed-author:SiZ DZD | lld:pubmed |
| pubmed-article:9267021 | pubmed:author | pubmed-author:LutschgAA | lld:pubmed |
| pubmed-article:9267021 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9267021 | pubmed:day | 8 | lld:pubmed |
| pubmed-article:9267021 | pubmed:volume | 90 | lld:pubmed |
| pubmed-article:9267021 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9267021 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9267021 | pubmed:pagination | 405-13 | lld:pubmed |
| pubmed-article:9267021 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:meshHeading | pubmed-meshheading:9267021-... | lld:pubmed |
| pubmed-article:9267021 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9267021 | pubmed:articleTitle | Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. | lld:pubmed |
| pubmed-article:9267021 | pubmed:affiliation | Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, 75235, USA. | lld:pubmed |
| pubmed-article:9267021 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9267021 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:9267021 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://bio2rdf.org/pubmed:9... | skos:relatedMatch | pubmed-article:9267021 | lld:mappings |
| entrez-gene:317 | entrezgene:pubmed | pubmed-article:9267021 | lld:entrezgene |
| entrez-gene:355 | entrezgene:pubmed | pubmed-article:9267021 | lld:entrezgene |
| entrez-gene:836 | entrezgene:pubmed | pubmed-article:9267021 | lld:entrezgene |
| entrez-gene:54205 | entrezgene:pubmed | pubmed-article:9267021 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:9267021 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:9267021 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9267021 | lld:pubmed |
