rdf:type |
|
lifeskim:mentions |
umls-concept:C0003250,
umls-concept:C0003316,
umls-concept:C0017968,
umls-concept:C0020792,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0043519,
umls-concept:C0053610,
umls-concept:C0086418,
umls-concept:C0330390,
umls-concept:C1135183,
umls-concept:C1334043,
umls-concept:C1421866
|
pubmed:issue |
1
|
pubmed:dateCreated |
1997-9-30
|
pubmed:abstractText |
Immunization with zona pellucida (ZP) glycoproteins leads to a block in fertility with a variable degree of ovarian dysfunction. To avoid autoimmune oophoritis, synthetic peptides corresponding to B cell epitope(s) and devoid of oophoritogenic T cell epitopes as immunogens have been proposed. The main objective of the present study is to define the epitopes recognized by monoclonal antibodies (mAbs) generated against porcine ZP3 beta, a homologue of the designated primary sperm receptor in mice and humans.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
1046-7408
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
38
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
26-32
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9266007-Amino Acid Sequence,
pubmed-meshheading:9266007-Animals,
pubmed-meshheading:9266007-Antibodies, Monoclonal,
pubmed-meshheading:9266007-B-Lymphocytes,
pubmed-meshheading:9266007-Binding Sites,
pubmed-meshheading:9266007-Egg Proteins,
pubmed-meshheading:9266007-Epitope Mapping,
pubmed-meshheading:9266007-Epitopes,
pubmed-meshheading:9266007-Humans,
pubmed-meshheading:9266007-Membrane Glycoproteins,
pubmed-meshheading:9266007-Mice,
pubmed-meshheading:9266007-Rabbits,
pubmed-meshheading:9266007-Receptors, Cell Surface,
pubmed-meshheading:9266007-Sequence Homology, Amino Acid,
pubmed-meshheading:9266007-Swine
|
pubmed:year |
1997
|
pubmed:articleTitle |
Identification of epitopes of monoclonal antibodies to porcine zona pellucida 3 beta glycoprotein, a homologue of the mouse/human sperm receptor.
|
pubmed:affiliation |
Gamete Antigen Laboratory, National Institute of Immunology, New Delhi, India.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|