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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1997-9-15
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pubmed:abstractText |
Idiopathic hypertrophic cardiomyopathy (HCM) is characterized by regional myocardial hypertrophy. To investigate involvement of growth factors on myocardial hypertrophy in HCM patients, we evaluated gene expression and cellular localization of transforming growth factor-beta1 (TGF-beta1), insulin-like growth factors (IGF-I and IGF-II), and platelet-derived growth factor-B (PDGF-B) in ventricular biopsies obtained from patients with HCM (n=8), aortic stenosis (AS) (n=8), or stable angina (SA) (n=8) and from explanted hearts with ischemic cardiomyopathy (TM) (n=7).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0009-7322
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
96
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
874-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9264495-Aged,
pubmed-meshheading:9264495-Angina Pectoris,
pubmed-meshheading:9264495-Aortic Valve Stenosis,
pubmed-meshheading:9264495-Cardiomyopathy, Hypertrophic,
pubmed-meshheading:9264495-Heart Ventricles,
pubmed-meshheading:9264495-Humans,
pubmed-meshheading:9264495-Immunohistochemistry,
pubmed-meshheading:9264495-In Situ Hybridization,
pubmed-meshheading:9264495-Insulin-Like Growth Factor I,
pubmed-meshheading:9264495-Male,
pubmed-meshheading:9264495-Middle Aged,
pubmed-meshheading:9264495-Myocardial Ischemia,
pubmed-meshheading:9264495-Myocardium,
pubmed-meshheading:9264495-Platelet-Derived Growth Factor,
pubmed-meshheading:9264495-Polymerase Chain Reaction,
pubmed-meshheading:9264495-Proto-Oncogene Proteins,
pubmed-meshheading:9264495-Proto-Oncogene Proteins c-sis,
pubmed-meshheading:9264495-Transcription, Genetic,
pubmed-meshheading:9264495-Transforming Growth Factor beta
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pubmed:year |
1997
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pubmed:articleTitle |
Overexpression of transforming growth factor-beta1 and insulin-like growth factor-I in patients with idiopathic hypertrophic cardiomyopathy.
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pubmed:affiliation |
Department of Clinical Biochemistry, and The Centre for Cardiovascular Research, The Toronto Hospital-General Division, University of Toronto, Ontario, Canada. rli@torhosp.toronto.on.ca
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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