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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1997-8-28
|
| pubmed:abstractText |
To clarify the seroprevalence of human T-cell lymphotropic virus type I (HTLV-I) among hematologic and cancer patients in the State of Rio de Janeiro, Brazil, we investigated sera from 2430 individuals from the following groups: 152 patients with T-cell diseases, 250 with B-cell disorders, 67 with myeloid leukemia, 41 with Hodgkin's disease, 351 with a history of multiple blood transfusions, 235 patients with solid tumors of different types, and 109 family members of HTLV-I-infected patients. Antibodies to HTLV-I were screened by enzyme-linked immunosorbent assay or particle agglutination assays (or both). Repeatedly reactive samples were tested by Western blot and polymerase chain reaction assay to differentiate HTLV-I from HTLV-II. We found an increased seroprevalence rate of HTLV-I among those with lymphoid malignancies, mainly in T-cell diseases (28.9%), and these results were important in characterizing 44 cases of adult T-cell leukemia/lymphoma. We confirmed the presence of HTLV-I and HTLV-II infections in blood donors (0.4% and 0.1%, respectively), in patients exposed to multiple blood transfusions (10.2% and 0.8%, respectively), and in 30 (27.5%) of 109 family members of HTLV-I- or HTLV-II-infected patients. We also confirmed the high rate occurrence of adult T-cell leukemia/lymphoma among lymphoproliferative disorders in Rio de Janeiro, Brazil.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
1077-9450
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
238-42
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9257659-Adolescent,
pubmed-meshheading:9257659-Adult,
pubmed-meshheading:9257659-Aged,
pubmed-meshheading:9257659-Aged, 80 and over,
pubmed-meshheading:9257659-Blood Donors,
pubmed-meshheading:9257659-Brazil,
pubmed-meshheading:9257659-DNA, Viral,
pubmed-meshheading:9257659-Female,
pubmed-meshheading:9257659-HTLV-I Antibodies,
pubmed-meshheading:9257659-HTLV-I Infections,
pubmed-meshheading:9257659-HTLV-II Antibodies,
pubmed-meshheading:9257659-HTLV-II Infections,
pubmed-meshheading:9257659-Hematologic Diseases,
pubmed-meshheading:9257659-Human T-lymphotropic virus 1,
pubmed-meshheading:9257659-Human T-lymphotropic virus 2,
pubmed-meshheading:9257659-Humans,
pubmed-meshheading:9257659-Male,
pubmed-meshheading:9257659-Middle Aged,
pubmed-meshheading:9257659-Neoplasms,
pubmed-meshheading:9257659-Prevalence,
pubmed-meshheading:9257659-Retrospective Studies
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
HTLV-I and HTLV-II infections in hematologic disorder patients, cancer patients, and healthy individuals from Rio de Janeiro, Brazil.
|
| pubmed:affiliation |
Cell Markers Laboratory of Instituto Nacional do Cancer, Rio de Janeiro, Brazil.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|