Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1997-9-19
|
| pubmed:abstractText |
CD4+ T cells can be divided into two major subsets, T helper (TH)1 and TH2 cells. Interleukin-4 (IL-4) is produced by TH2 cells and induces switching of immunoglobulin (Ig) M/IgG to IgE. Interferon-gamma (IFNgamma) produced by TH1 cells counteracts the IgE-promoting effects of IL-4. In this study we wanted to investigate whether the number of IL-4-producing cells could be a direct measurement of allergen exposure in vitro, and whether this was correlated to the elevated serum IgE-levels seen in atopic persons.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0954-7894
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
27
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
808-15
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9249274-Adult,
pubmed-meshheading:9249274-Allergens,
pubmed-meshheading:9249274-Animals,
pubmed-meshheading:9249274-Cats,
pubmed-meshheading:9249274-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:9249274-Humans,
pubmed-meshheading:9249274-Hypersensitivity, Immediate,
pubmed-meshheading:9249274-Immunoglobulin E,
pubmed-meshheading:9249274-Interleukin-4,
pubmed-meshheading:9249274-Leukocytes, Mononuclear,
pubmed-meshheading:9249274-Middle Aged,
pubmed-meshheading:9249274-Trees
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Specific induction of interleukin-4-producing cells in response to in vitro allergen stimulation in atopic individuals.
|
| pubmed:affiliation |
Department of Immunology, Stockholm University, Sweden.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|