rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1997-8-22
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pubmed:databankReference |
|
pubmed:abstractText |
A cDNA clone encoding rat p130, a member of the retinoblastoma (Rb) gene family, was isolated based on the sequence homology of the E1A-binding domain. The 4.87 kb cDNA contained an 1135-amino acid open reading frame with high homologies to the human and mouse p130 and a partial homology to the pRb protein. p130 showed difference in distribution of potential phosphorylation sites from pRb in the N-terminal and the B pocket regions. p130 mRNA was detected in most rat tissues. The p130 gene was mapped to rat chromosome 19p11-13 by fluorescence in situ hybridization.
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0006-3002
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
10
|
pubmed:volume |
1361
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
20-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9247086-Amino Acid Sequence,
pubmed-meshheading:9247086-Animals,
pubmed-meshheading:9247086-Base Sequence,
pubmed-meshheading:9247086-Cloning, Molecular,
pubmed-meshheading:9247086-DNA, Complementary,
pubmed-meshheading:9247086-In Situ Hybridization, Fluorescence,
pubmed-meshheading:9247086-Molecular Sequence Data,
pubmed-meshheading:9247086-Phosphoproteins,
pubmed-meshheading:9247086-Proteins,
pubmed-meshheading:9247086-Rats,
pubmed-meshheading:9247086-Retinoblastoma,
pubmed-meshheading:9247086-Retinoblastoma-Like Protein p130,
pubmed-meshheading:9247086-Sequence Homology, Nucleic Acid
|
pubmed:year |
1997
|
pubmed:articleTitle |
Cloning and characterization of the rat p130, a member of the retinoblastoma gene family.
|
pubmed:affiliation |
Department of Molecular Biology, Cancer Research Institute, Sapporo Medical University School of Medicine, Japan. ysawada@sapmed.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|