Linked Life Data

9246028

Source:http://linkedlifedata.com/resource/pubmed/id/9246028

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1997-8-25
pubmed:abstractText
An abnormal score during 24-hr esophageal pH monitoring in achalasia may be associated either with a slow steady drift to below pH 4, or else multiple sharp dips characteristic of typical gastroesophageal reflux. To test the hypothesis that the former pattern was due to food fermentation and not reflux, samples of chewed bland food (N = 22) were incubated with saliva at 37 degrees C for 24 hr and the pH monitored (in vitro study). Further, the pH tracings of 20 patients with achalasia before operation and 12 patients after operation were studied (in vivo study). The pH of chewed food fell to a median of pH 4.0 during incubation and in seven of 22 samples fell to below pH 4. Preoperatively, four of the five patients with an abnormal pH score showed a slow steady drift, and all of these had evidence of retained food at endoscopy. Postoperatively, three of the six patients with an abnormal pH score had a slow steady drift to below pH 4. Use of pH 3 as a threshold clearly distinguished true reflux from food fermentation, since the patients with reflux all had an abnormal percentage of time below pH 3.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0163-2116
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1354-61
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Gastroesophageal reflux in achalasia. When is reflux really reflux?
pubmed:affiliation
University of Southern California School of Medicine, Department of Surgery, Los Angeles 90033-4612, USA.
pubmed:publicationType
Journal Article