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rdf:type |
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lifeskim:mentions |
umls-concept:C0007452,
umls-concept:C0033268,
umls-concept:C0035647,
umls-concept:C0035820,
umls-concept:C0038836,
umls-concept:C0131722,
umls-concept:C0202155,
umls-concept:C0225828,
umls-concept:C0376261,
umls-concept:C0391840,
umls-concept:C0483414
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pubmed:issue |
2
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|
pubmed:dateCreated |
1997-8-26
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|
pubmed:abstractText |
Lactate increases lucigenin chemiluminescence (CL)-detectable superoxide anion (O2.-) generation in bovine vascular smooth muscle and endothelium, and a microsomal flavoprotein-containing NADH oxidase whose activity is regulated by PO2 and cytosolic NAD(H) redox appears to be the detected source of O2.- production. Little is known about the importance of this O2.(-)-producing system in cardiac myocytes.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
|
pubmed:issn |
0009-7322
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
96
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
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pubmed:pagination |
614-20
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9244234-Animals,
pubmed-meshheading:9244234-Cattle,
pubmed-meshheading:9244234-Cells, Cultured,
pubmed-meshheading:9244234-Free Radicals,
pubmed-meshheading:9244234-Lactic Acid,
pubmed-meshheading:9244234-Multienzyme Complexes,
pubmed-meshheading:9244234-Myocardium,
pubmed-meshheading:9244234-NADH, NADPH Oxidoreductases,
pubmed-meshheading:9244234-Reactive Oxygen Species,
pubmed-meshheading:9244234-Superoxides
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pubmed:year |
1997
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|
pubmed:articleTitle |
Lactate and PO2 modulate superoxide anion production in bovine cardiac myocytes: potential role of NADH oxidase.
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|
pubmed:affiliation |
Department of Physiology, New York Medical College, Valhalla, NY 10595, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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