Linked Life Data

9239504

Source:http://linkedlifedata.com/resource/pubmed/id/9239504

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1997-9-3
pubmed:abstractText
Interferon-alpha (IFN-alpha) is a protein family controlled by altogether 26 different IFN-alpha genes. We have previously described an SspI polymorphism in the IFN A17 gene and an association between the SspI A2 allele and nasopharyngeal cancer. In this paper we present data on ethnic differences with respect to IFN A17 SspI allele frequencies. Thus the frequency of the SspI A1 allele was high in two different Chinese populations (51 and 48%, respectively) and much lower (11%) in Swedes. Intermediate values were found in African Blacks (32%), Indians (25%), Saamis (29%) and Finns (24%). The very pronounced differences between major ethnic groups make the IFN A17 SspI polymorphism a very informative anthropological marker system and suggest that it may be balanced and maintained by natural selection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5652
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
185-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Ethnic differences in interferon-alpha allele frequencies.
pubmed:affiliation
Department of Medical Genetics, Umeå University, Sweden.
pubmed:publicationType
Journal Article