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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1997-8-14
|
| pubmed:abstractText |
Nonhabituation of the acoustic startle response is used to identify rat subjects with altered alarm responses subsequent to trauma exposure. Subjects (n = 31) were exposed to 30 minutes of intermittent tail shock on 2 days followed by exposure to the apparatus on the third day. Twenty-nine percent of traumatized rats developed nonhabituation of startle over the subsequent 3 weeks of testing. No control rats developed nonhabituation of startle reactions over a similar time period. These data suggest that this system represents a more accurate representation of clinical PTSD than do other animal models.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0077-8923
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
21
|
| pubmed:volume |
821
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
533-7
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9238246-Animals,
pubmed-meshheading:9238246-Disease Models, Animal,
pubmed-meshheading:9238246-Rats,
pubmed-meshheading:9238246-Rats, Sprague-Dawley,
pubmed-meshheading:9238246-Startle Reaction,
pubmed-meshheading:9238246-Stress, Psychological,
pubmed-meshheading:9238246-Stress Disorders, Post-Traumatic
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Psychophysiologic parameters of traumatic stress disorder in rats.
|
| pubmed:affiliation |
West Los Angeles VA Medical Center, California, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
|