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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1997-8-21
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pubmed:abstractText |
The effect of long-term oral iron supplementation on morbidity due to diarrhea, dysentery and respiratory infections in 349 children, aged 2-48 mo, living in a poor community of Bangladesh, was evaluated in this double-blind study. The treatment group received 125 mg of ferrous gluconate (15 mg elemental iron) plus multivitamins and the controls received only multivitamins, daily for 15 mo. House-to-house visits were made on alternate days by trained community health workers for recording symptoms and duration of illnesses and for monitoring medicine intake. Seventy-six percent of the children continued the syrup for over 1 y. No untoward effects were noticed in either treatment group. The attack rates for diarrhea, dysentery and acute respiratory tract infections (ARI) were 3, 3 and 5 episodes per child per year, respectively. Each episode of diarrhea lasted a mean of 3 d, and those of dysentery and ARI, 5 d. The two treatment groups did not differ in the number of episodes, mean duration of each episode, or total days of illnesses due to diarrhea, dysentery and ARI. However, a 49% greater number of episodes of dysentery was observed with iron supplementation in a subset of the study children who were less than 12 mo old (P = 0.03). The results of this study suggest that long-term oral iron supplementation is not harmful for older children in a poor community. Further studies are needed to demonstrate the safety and efficacy of iron administration in young infants.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-3166
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
127
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1451-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9237937-Administration, Oral,
pubmed-meshheading:9237937-Bangladesh,
pubmed-meshheading:9237937-Child, Preschool,
pubmed-meshheading:9237937-Diarrhea,
pubmed-meshheading:9237937-Drug Interactions,
pubmed-meshheading:9237937-Dysentery,
pubmed-meshheading:9237937-Female,
pubmed-meshheading:9237937-Ferrous Compounds,
pubmed-meshheading:9237937-Humans,
pubmed-meshheading:9237937-Infant,
pubmed-meshheading:9237937-Male,
pubmed-meshheading:9237937-Poverty,
pubmed-meshheading:9237937-Prospective Studies,
pubmed-meshheading:9237937-Respiratory Tract Infections,
pubmed-meshheading:9237937-Vitamins
|
pubmed:year |
1997
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pubmed:articleTitle |
Long-term oral supplementation with iron is not harmful for young children in a poor community of Bangladesh.
|
pubmed:affiliation |
International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka 1212, Bangladesh.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|