Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1997-10-23
pubmed:abstractText
Human granulocytic ehrlichiosis (HGE) and Lyme disease are caused by infectious agents transmitted by deer ticks (Ixodes scapularis). Because of the shared tick vector and increased seroprevalence of HGE in patients with Lyme disease, there is some confusion about the identity of these infectious agents and the clinicopathologic spectrum of the disease. HGE is an acute febrile illness associated with leukopenia, thrombocytopenia, and increased serum activities of hepatic transaminases. In contrast, Lyme disease is most often subacute, with the frequent presence of erythema migrans rash and infrequent leukopenia, thrombocytopenia, or elevated serum hepatic transaminase activities. Some ehrlichia infections in animals and humans may become persistent, and Ehrlichia-mediated defects in host defense and immune suppression can allow secondary and opportunistic infections. Because of these properties of Ehrlichia species, their role in modifying the clinical course of Lyme disease may be hypothesized and should be tested.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1058-4838
pubmed:author
pubmed:issnType
Print
pubmed:volume
25 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S43-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Is human granulocytic ehrlichiosis a new Lyme disease? Review and comparison of clinical, laboratory, epidemiological, and some biological features.
pubmed:affiliation
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't