Linked Life Data

9233543

Source:http://linkedlifedata.com/resource/pubmed/id/9233543

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-9-12
pubmed:abstractText
In spite of its association by history and name to platelets, platelet-derived growth factor (PDGF) exerts important actions in a myriad of tissues, including the nervous system. PDGF and PDGF receptors are widely expressed in neuronal and glial cells of many regions of both the central and peripheral nervous systems. In this topical review, the roles played by PDGF in the development and maintenance of the nervous system are discussed. We also discuss the modulatory effects of PDGF on synaptic transmission, its role in neoplastic and non-neoplastic conditions of the central nervous system, and the neuroprotective effects of this growth factor.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:author
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
77-89
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Roles of platelet-derived growth factor in the developing and mature nervous systems.
pubmed:affiliation
Department of Pharmacology, University of Colorado Health Sciences Center, Denver 80262, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review