Linked Life Data

9232356

Source:http://linkedlifedata.com/resource/pubmed/id/9232356

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-9-12
pubmed:abstractText
The autonomic nervous system has an important role in the pathophysiology of vasovagal syncope. The purpose of this investigation was to evaluate to what extent the autonomic system is involved in the mechanism of fainting and to characterize the profile of heart rate variability of individuals who are prone to undergo a critical event. Thirty patients (mean age 41 years) with vasovagal syncope and 15 comparable controls were monitored by 24-h electrocardiography. Heart rate variability was analysed over the whole 24 h and during the daytime and night-time using time domain parameters (average of heart periods, RR; standard deviation of heart periods, SDNN; standard deviation of the average of RR intervals over all the 5-min segments of the entire recording, SDANN; percentage of the total number of all RR intervals of pairs of adjacent RR intervals differing more than 50 ms over the entire recording, pNN50; the square root of the sum of the square of differences between adjacent RR intervals, rMSSD), as indicated by the Task Force for Clinical Use of Standard Measurements of Heart Rate Variability. These parameters explore the influence of the autonomic nervous system on sinus node function and provide information about the vagal control to the heart. Among these parameters, pNN50 and rMSSD were significantly reduced in individuals with vasovagal syncope when compared with controls, over each time period considered. The two parameters are related to high-frequency oscillations in the frequency domain and to the vagal influence of the heart. These results indicate that the vagal tone to the heart is altered in subjects who suffer from vasovagal syncope. The results of this study provide an insight into the pathophysiological mechanism of fainting and may offer another means of evaluating patients with syncope.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0959-9851
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
127-30
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Vagal control of heart rate variability in vasovagal syncope: studies based on 24-h electrocardiogram recordings.
pubmed:affiliation
Internal Medicine Department, Santa Maria Nuova Hospital, Florence, Italy.
pubmed:publicationType
Journal Article, Clinical Trial