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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-9-4
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pubmed:abstractText |
This study included 54 unselected patients with rheumatic heart disease (RHD) with or without history of rheumatic fever and 224 control subjects, all Kashmiris. HLA-A19 was increased in 42.59 percent of patient population as against 23.66 percent of controls, with a relative risk of 2.39. HLA-DR4 was positive in 56 percent of patients as against 31.69 percent in controls with a relative risk of 2.74. DQ3 was also present in 72 percent of patient population as against 50.7 percent of controls. These findings suggest a genetic predisposition to rheumatic fever/RHD. More family studies are warranted.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0019-4832
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
152-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9231545-Adult,
pubmed-meshheading:9231545-Chronic Disease,
pubmed-meshheading:9231545-Female,
pubmed-meshheading:9231545-Gene Frequency,
pubmed-meshheading:9231545-HLA Antigens,
pubmed-meshheading:9231545-HLA-A Antigens,
pubmed-meshheading:9231545-HLA-B Antigens,
pubmed-meshheading:9231545-HLA-C Antigens,
pubmed-meshheading:9231545-HLA-DQ Antigens,
pubmed-meshheading:9231545-HLA-DR Antigens,
pubmed-meshheading:9231545-Humans,
pubmed-meshheading:9231545-India,
pubmed-meshheading:9231545-Male,
pubmed-meshheading:9231545-Middle Aged,
pubmed-meshheading:9231545-Rheumatic Heart Disease
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pubmed:articleTitle |
Study of HLA-A, B, C, DR, DQ profile of patients with established rheumatic heart disease in Kashmir.
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pubmed:affiliation |
Department of Medicine, Riyadh Medical Complex, KSA.
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pubmed:publicationType |
Journal Article
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