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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1997-8-21
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pubmed:abstractText |
Today there is considerable interest in oral peptide delivery. However, oral administration of peptides is limited by a low bioavailability and a high variability in plasma levels. A review is given of the literature describing the major barriers in peptide absorption, the basic mechanisms of intestinal peptide transport, the experimental models and the pharmaceutical approaches currently used in the investigation of peptide and protein absorption processes.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
1075-2617
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
195-211
|
pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9231327-Animals,
pubmed-meshheading:9231327-Biological Transport,
pubmed-meshheading:9231327-Chemistry, Pharmaceutical,
pubmed-meshheading:9231327-Chemistry, Physical,
pubmed-meshheading:9231327-Humans,
pubmed-meshheading:9231327-Intestinal Absorption,
pubmed-meshheading:9231327-Peptides,
pubmed-meshheading:9231327-Physicochemical Phenomena,
pubmed-meshheading:9231327-Proteins
|
pubmed:articleTitle |
Current concepts in intestinal peptide absorption.
|
pubmed:affiliation |
Institut für Pharmazeutische Technologie und Biopharmazie, Ruprecht-Karls-Universität, Heidelberg, Germany. jw3@ix.urz.uni.heidelberg.de
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pubmed:publicationType |
Journal Article,
Review
|