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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1997-9-18
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pubmed:abstractText |
Sympathetic cardiac denervation of the transplanted human heart causes a loss of the presynaptic neuronal uptake1-mechanism with consecutive supersensitivity to uptake1-dependent catecholamines. A return of neuronal function (reinnervation) should result in a decrease of supersensitivity to catecholamines subjected to this uptake system and thus may alter the inotropic regulation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1053-2498
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
621-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9229292-Adrenergic alpha-Agonists,
pubmed-meshheading:9229292-Adrenergic beta-Agonists,
pubmed-meshheading:9229292-Adult,
pubmed-meshheading:9229292-Aged,
pubmed-meshheading:9229292-Blood Pressure,
pubmed-meshheading:9229292-Denervation,
pubmed-meshheading:9229292-Dose-Response Relationship, Drug,
pubmed-meshheading:9229292-Echocardiography,
pubmed-meshheading:9229292-Epinephrine,
pubmed-meshheading:9229292-Female,
pubmed-meshheading:9229292-Follow-Up Studies,
pubmed-meshheading:9229292-Heart,
pubmed-meshheading:9229292-Heart Rate,
pubmed-meshheading:9229292-Heart Transplantation,
pubmed-meshheading:9229292-Humans,
pubmed-meshheading:9229292-Isoproterenol,
pubmed-meshheading:9229292-Male,
pubmed-meshheading:9229292-Middle Aged,
pubmed-meshheading:9229292-Myocardial Contraction,
pubmed-meshheading:9229292-Nerve Regeneration,
pubmed-meshheading:9229292-Postoperative Complications,
pubmed-meshheading:9229292-Presynaptic Terminals,
pubmed-meshheading:9229292-Receptors, Presynaptic,
pubmed-meshheading:9229292-Sympathetic Nervous System
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pubmed:year |
1997
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pubmed:articleTitle |
Time-dependent decrease of presynaptic inotropic supersensitivity: physiological evidence of sympathetic reinnervation after heart transplantation.
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pubmed:affiliation |
Medizinische Klinik I, University of Munich, Germany.
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pubmed:publicationType |
Journal Article
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