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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1997-8-12
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pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D10072,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/J04324,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/K02734,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M20304,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M20869,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M22138,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M33879,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M65834,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/U34248,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/U70799,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/U70800,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/U70801,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/U70802,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/U70803,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/U70804,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/X52400,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/X62616
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pubmed:abstractText |
The Junin virus strain Candid #1 was developed as a live attenuated vaccine for Argentine haemorrhagic fever. In this paper we report the nucleotide sequences of S RNA of Candid #1 and its more virulent ancestors XJ#44 and XJ (prototype). Their relationship to Junin virus wild-type MC2 strain and other closely and distantly related arenaviruses was also examined. Comparisons of the nucleotide and amino acid sequences of N and GPC genes from Candid #1 and its progenitor strains revealed some changes that are unique to the vaccine strain. These changes could be provisionally associated with the attenuated phenotype.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-1317
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
78 ( Pt 7)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1605-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9225036-Amino Acid Sequence,
pubmed-meshheading:9225036-Animals,
pubmed-meshheading:9225036-Cell Line,
pubmed-meshheading:9225036-Cricetinae,
pubmed-meshheading:9225036-Humans,
pubmed-meshheading:9225036-Junin virus,
pubmed-meshheading:9225036-Molecular Sequence Data,
pubmed-meshheading:9225036-Nucleocapsid,
pubmed-meshheading:9225036-RNA, Viral,
pubmed-meshheading:9225036-Sequence Homology, Amino Acid,
pubmed-meshheading:9225036-Vaccines, Attenuated,
pubmed-meshheading:9225036-Viral Envelope Proteins,
pubmed-meshheading:9225036-Viral Vaccines
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pubmed:year |
1997
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pubmed:articleTitle |
Molecular characterization of attenuated Junin virus strains.
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pubmed:affiliation |
Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Argentina.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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