|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007117,
umls-concept:C0007589,
umls-concept:C0035647,
umls-concept:C0038128,
umls-concept:C0079850,
umls-concept:C0205126,
umls-concept:C0205155,
umls-concept:C0221971,
umls-concept:C0449435,
umls-concept:C1511938,
umls-concept:C1514485,
umls-concept:C1522472,
umls-concept:C1524063,
umls-concept:C1551341,
umls-concept:C1552858,
umls-concept:C1552923,
umls-concept:C1552924,
umls-concept:C1705191
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
1997-7-30
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|
pubmed:abstractText |
Histopathologic differentiation between benign and malignant tissue is of utmost importance for the Mohs surgeon. Folliculocentric basaloid proliferation (FBP) shares many histologic features with basal cell carcinoma (BCC). It is most commonly associated with tumors of areas with abundant hair follicles such as nasal and perinasal skin. Residual BCC incorrectly identified as a horizontally sectioned hair follicle undoubtedly increases the risk of tumor recurrence. Excision of additional layers of normal tissue to remove "funny looking follicles" may have profound impacts on tissue conservation, preservation of function, and cosmesis. Electron microscope studies of BCC revealed a significant reduction of desmosomes compared with normal basal cells and hair follicle keratinocytes.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
1076-0512
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
23
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
463-8
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|
pubmed:dateRevised |
2005-11-17
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|
pubmed:meshHeading |
pubmed-meshheading:9217798-Aged,
pubmed-meshheading:9217798-Aged, 80 and over,
pubmed-meshheading:9217798-Antibodies, Monoclonal,
pubmed-meshheading:9217798-Carcinoma, Basal Cell,
pubmed-meshheading:9217798-Cell Division,
pubmed-meshheading:9217798-Cytoskeletal Proteins,
pubmed-meshheading:9217798-Desmogleins,
pubmed-meshheading:9217798-Desmoplakins,
pubmed-meshheading:9217798-Female,
pubmed-meshheading:9217798-Hair Diseases,
pubmed-meshheading:9217798-Hair Follicle,
pubmed-meshheading:9217798-Humans,
pubmed-meshheading:9217798-Immunoenzyme Techniques,
pubmed-meshheading:9217798-Male,
pubmed-meshheading:9217798-Middle Aged,
pubmed-meshheading:9217798-Mohs Surgery,
pubmed-meshheading:9217798-Skin Neoplasms
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|
pubmed:year |
1997
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|
pubmed:articleTitle |
The use of antidesmoglein stains in Mohs micrographic surgery. A potential aid for the differentiation of basal cell carcinoma from horizontal sections of the hair follicle and folliculocentric basaloid proliferation.
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|
pubmed:affiliation |
Dermatologic Surgery Unit, Duke University Medical Center, Durham, North Carolina 27710, USA.
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pubmed:publicationType |
Journal Article
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