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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1997-9-2
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pubmed:abstractText |
We assessed the day-to-day reproducible of vitreous fluorophotometry in 7 type 1 diabetic patients and in 1 healthy control subject. The coefficient of variation for duplicate measurements was 33.7, 40.3 and 23.6%, for the right eyes, the left eyes and mean values of both eyes, respectively. Assessment of reproducibility in 1 healthy subject, measured 4 times, resulted in coefficients of variation of about 60%. These values are somewhat worse than those obtained by others in healthy subjects. Since technical problems do not seem to play a significant role in this regard, our reproducibility results reflect the true biological variability of the permeability of the blood-retina barrier assessed by vitreous fluorophotometry in diabetic patients. This variability is substantial. Therefore, we conclude that this method is not precise enough to be used in intervention studies with a limited number of subjects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0030-3755
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
211
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
209-13
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pubmed:dateRevised |
2007-9-17
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pubmed:meshHeading |
pubmed-meshheading:9216008-Adult,
pubmed-meshheading:9216008-Aged,
pubmed-meshheading:9216008-Blood-Retinal Barrier,
pubmed-meshheading:9216008-Cryopreservation,
pubmed-meshheading:9216008-Diabetes Mellitus, Type 1,
pubmed-meshheading:9216008-Female,
pubmed-meshheading:9216008-Fluorescein,
pubmed-meshheading:9216008-Fluoresceins,
pubmed-meshheading:9216008-Fluorophotometry,
pubmed-meshheading:9216008-Freezing,
pubmed-meshheading:9216008-Humans,
pubmed-meshheading:9216008-Male,
pubmed-meshheading:9216008-Middle Aged,
pubmed-meshheading:9216008-Reference Values,
pubmed-meshheading:9216008-Reproducibility of Results,
pubmed-meshheading:9216008-Vitreous Body
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pubmed:year |
1997
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pubmed:articleTitle |
Reproducibility of vitreous fluorophotometry in patients with type 1 diabetes mellitus.
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pubmed:affiliation |
St. Lucas Ziekenhuis, Winschoten.
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pubmed:publicationType |
Journal Article
|