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rdf:type |
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lifeskim:mentions |
umls-concept:C0006142,
umls-concept:C0014582,
umls-concept:C0031327,
umls-concept:C0040808,
umls-concept:C0144576,
umls-concept:C0205179,
umls-concept:C0205251,
umls-concept:C0441655,
umls-concept:C0876994,
umls-concept:C1442460,
umls-concept:C2603343
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|
pubmed:issue |
7
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pubmed:dateCreated |
1997-7-25
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pubmed:abstractText |
To determine the maximum-tolerated dose (MTD) of paclitaxel over 3 hours with a fixed dose of epirubicin, to investigate the plasma pharmacokinetics of this combination, and to evaluate the toxicity and the activity in previously untreated metastatic breast cancer patients.
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|
pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0732-183X
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pubmed:author |
pubmed-author:BaldiniEE,
pubmed-author:BiadiOO,
pubmed-author:DanesiRR,
pubmed-author:Del TaccaMM,
pubmed-author:Dell'AnnaRR,
pubmed-author:GennariAA,
pubmed-author:GentileAA,
pubmed-author:InnocentiFF,
pubmed-author:MarianiMM,
pubmed-author:MichelottiAA,
pubmed-author:SalvadoriBB,
pubmed-author:TibaldiCC,
pubmed-author:YonemitsuHH
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2510-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9215819-Adult,
pubmed-meshheading:9215819-Aged,
pubmed-meshheading:9215819-Antibiotics, Antineoplastic,
pubmed-meshheading:9215819-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:9215819-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:9215819-Breast Neoplasms,
pubmed-meshheading:9215819-Drug Administration Schedule,
pubmed-meshheading:9215819-Epirubicin,
pubmed-meshheading:9215819-Female,
pubmed-meshheading:9215819-Heart Diseases,
pubmed-meshheading:9215819-Humans,
pubmed-meshheading:9215819-Least-Squares Analysis,
pubmed-meshheading:9215819-Middle Aged,
pubmed-meshheading:9215819-Neutropenia,
pubmed-meshheading:9215819-Paclitaxel,
pubmed-meshheading:9215819-Prospective Studies,
pubmed-meshheading:9215819-Stroke Volume,
pubmed-meshheading:9215819-Survival Analysis,
pubmed-meshheading:9215819-Treatment Outcome
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pubmed:year |
1997
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pubmed:articleTitle |
Dose-finding study and pharmacokinetics of epirubicin and paclitaxel over 3 hours: a regimen with high activity and low cardiotoxicity in advanced breast cancer.
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pubmed:affiliation |
Division of Medical Oncology, Oncologia Medica, Ospedale S. Chiara, Pisa, Italy.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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