Linked Life Data

920976

Source:http://linkedlifedata.com/resource/pubmed/id/920976

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1977-12-29
pubmed:abstractText
In an attempt to localize the site of remodelling of collagen in the periodontal ligament of the continuously erupting mouse incisor a radioautographic and stereologic investigation was undertaken. Grain distributions in radioautographs for light microscopy were studied at various time intervals after administration of [3H]-proline. The distribution of rough endoplasmic reticulum cisternae in fibroblasts and the incidence of collagen phagocytosis across the ligament were studied by means of stereologic methods at the electron microscopic level. No significant differences were found in half lives of [3H]-labelled substances among the various regions across the ligament. Rough endoplasmic reticulum cisternae within fibroblasts were distributed more or less uniformly throughout the entire width of the ligament. Analysis of the distribution of collagen phagocytosis, however, revealed that in the midregion of the ligament the amount of phagocytosed collagen was approximately four times as high as in the area adjacent to the tooth and about nine times as high as in the alveolar compartment. It is concluded that synthesis and turnover of total protein occurs throughout the periodontal ligament but that remodelling of collagen predominantly takes place in an intermediate area of the ligament.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0003-276X
pubmed:author
pubmed:issnType
Print
pubmed:volume
189
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
479-97
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
The site of remodeling of collagen in the periodontal ligament of the mouse incisor.
pubmed:publicationType
Journal Article