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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1997-7-15
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pubmed:abstractText |
Platelets isolated from patients with hypercholesterolemia are more sensitive in vitro to various aggregating agents, including epinephrine, than those isolated from normocholesterolemic subjects. Increased platelet reactivity is one mechanism that may explain the enhanced risk of thromboembolism in hypercholesterolemia. This study assessed whether platelet hyperreactivity to epinephrine in hypercholesterolemia is associated with higher alpha 2-adrenergic receptor density or affinity for epinephrine.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0009-9236
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
684-91
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9209252-Adrenergic alpha-Antagonists,
pubmed-meshheading:9209252-Adult,
pubmed-meshheading:9209252-Aged,
pubmed-meshheading:9209252-Case-Control Studies,
pubmed-meshheading:9209252-Epinephrine,
pubmed-meshheading:9209252-Female,
pubmed-meshheading:9209252-Humans,
pubmed-meshheading:9209252-Hypercholesterolemia,
pubmed-meshheading:9209252-Lipids,
pubmed-meshheading:9209252-Male,
pubmed-meshheading:9209252-Middle Aged,
pubmed-meshheading:9209252-Platelet Aggregation,
pubmed-meshheading:9209252-Receptors, Adrenergic, alpha-2,
pubmed-meshheading:9209252-Yohimbine
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pubmed:year |
1997
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pubmed:articleTitle |
Platelet alpha 2-adrenergic receptors in hypercholesterolemia: relationship between binding studies and epinephrine-induced platelet aggregation.
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pubmed:affiliation |
Enrica Grossi Paoletti Center, Institute of Pharmacological Sciences, University of Milan, Italy.
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pubmed:publicationType |
Journal Article
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