Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-7-15
pubmed:abstractText
Segregation ratio, heritability and relative risk of genetic susceptibility were estimated for 355 families of lung cancer in matched pair with genetic epidemiological methods. Results showed that segregation ratio for lung cancer was 0.09-0.12 (95% confidence interval, CI) and heritability of lung cancer was (40.58 +/- 4.01)% and (27.58 +/- 4.76)% for smokers and non-smokers, respectively. Relative risks of genetic susceptibility to lung cancer were 4.73 (95% CI 3.90-5.74) and 2.61 (95% CI 2.18-3.13) in their first and second degree relatives, respectively, after adjustment of smoking with a logistic regression model. It was also found that there was an interaction between smoking habit and genetic background of lung cancer. Thus, it is believed that genetic background is one of the multifactorial causes in lung cancer.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0253-9624
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
154-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
[A genetic epidemiological study on lung cancer].
pubmed:affiliation
Department of Epidemiology, Suzhou Medical College.
pubmed:publicationType
Journal Article, English Abstract