Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-7-22
pubmed:abstractText
The chemotherapy side-effects are insufficiently documented while they strongly condition patients' quality of life. The aim of the study was to assess by means of a self-administered questionnaire the somatic symptoms experienced by breast cancer patients during their NCF (mitoxantrone + cyclophosphamide + 5-fluorouracil) chemotherapy and to demonstrate the interest of this self-report by comparing the frequency of side-effects assessed by the patients to that noted by the physicians in medical records. The study was carried out among 44 patients receiving their chemotherapy + radiotherapy at the Paoli-Calmettes Institute (marseille) between July 1994 and May 1995. The questionnaire comprized of 17 symptoms evaluated in terms of frequency, duration/severity and distress. The most frequent symptoms are: hair loss and nausea (75%), hot flush (57%), lack of appetite and headache (46%) associated with distress in 67 to 100% of cases. Their frequency was underestimated by the physicians in medical records. This study showed a large discordance patient-physician in the assessment of chemotherapy side-effects. The type of tool presented in this study could complement the usual scales of toxicity that do not provide an estimation of true patients' experience.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0007-4551
pubmed:author
pubmed:issnType
Print
pubmed:volume
84
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
240-6
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:9207868-Adult, pubmed-meshheading:9207868-Aged, pubmed-meshheading:9207868-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:9207868-Breast Neoplasms, pubmed-meshheading:9207868-Combined Modality Therapy, pubmed-meshheading:9207868-Cyclophosphamide, pubmed-meshheading:9207868-Data Interpretation, Statistical, pubmed-meshheading:9207868-Female, pubmed-meshheading:9207868-Fluorouracil, pubmed-meshheading:9207868-Humans, pubmed-meshheading:9207868-Middle Aged, pubmed-meshheading:9207868-Mitoxantrone, pubmed-meshheading:9207868-Neoplasm Staging, pubmed-meshheading:9207868-Physician-Patient Relations, pubmed-meshheading:9207868-Quality of Life, pubmed-meshheading:9207868-Questionnaires, pubmed-meshheading:9207868-Self-Assessment, pubmed-meshheading:9207868-Treatment Outcome
pubmed:year
1997
pubmed:articleTitle
[Adjuvant chemotherapy with mitoxantrone, cyclophosphamide and 5-fluorouracil in breast neoplasms: therapeutic life].
pubmed:affiliation
Institut Paoli-Calmettes, Marseille, France.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't