Linked Life Data

9207207

Source:http://linkedlifedata.com/resource/pubmed/id/9207207

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-7-24
pubmed:abstractText
Use of the fragrance 6-methylcoumarin (6-MC) in cosmetic products has declined significantly due to numerous reports of photoallergic contact dermatitis associated with its use. We have determined that 6-MC undergoes direct photolysis with an estimated half-life of 83 minutes when illuminated with mid-latitude U.S., noon-centered, equinox sunlight and a quantum yield for photolysis at 313 nm of phi = 3 x 10(-3). The work presented here also provides evidence that singlet molecular oxygen ((1)O2) is formed in illuminated solutions containing 6-MC. An estimated value of phi = 0.01 is reported for the (1)O2 quantum yield at 313 nm. Formation of (1)O2 is significant because it is known to react with a variety of biomolecules and it is possible that (1)O2 formation is at least partially responsible for reports of 6-MC photoallergenicity and phototoxicity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-291X
pubmed:author
pubmed:issnType
Print
pubmed:day
27
pubmed:volume
235
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
615-8
pubmed:dateRevised
2001-11-2
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Photochemical formation of singlet molecular oxygen ((1)O2) in illuminated 6-methylcoumarin solutions.
pubmed:affiliation
Department of Health and Safety, Indiana State University, Terre Haute 47809, USA.
pubmed:publicationType
Journal Article