Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1997-9-19
pubmed:abstractText
In men, the inflammatory response to intravenous endotoxin depresses apparent oral clearances of antipyrine, hexobarbitone, and theophylline. The aim of this study was to investigate whether there might be gender differences in the regulation of hepatic cytochromes P450.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Inflammatory Agents..., http://linkedlifedata.com/resource/pubmed/chemical/Antipyrine, http://linkedlifedata.com/resource/pubmed/chemical/C-Reactive Protein, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System, http://linkedlifedata.com/resource/pubmed/chemical/Hexobarbital, http://linkedlifedata.com/resource/pubmed/chemical/Hypnotics and Sedatives, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6, http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides, http://linkedlifedata.com/resource/pubmed/chemical/Phosphodiesterase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Theophylline, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0306-5251
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
627-32
pubmed:dateRevised
2009-10-2
pubmed:meshHeading
pubmed-meshheading:9205823-Adult, pubmed-meshheading:9205823-Anti-Inflammatory Agents, Non-Steroidal, pubmed-meshheading:9205823-Antipyrine, pubmed-meshheading:9205823-Area Under Curve, pubmed-meshheading:9205823-C-Reactive Protein, pubmed-meshheading:9205823-Cytochrome P-450 Enzyme System, pubmed-meshheading:9205823-Female, pubmed-meshheading:9205823-Fever, pubmed-meshheading:9205823-Hexobarbital, pubmed-meshheading:9205823-Humans, pubmed-meshheading:9205823-Hypnotics and Sedatives, pubmed-meshheading:9205823-Interleukin-6, pubmed-meshheading:9205823-Lipopolysaccharides, pubmed-meshheading:9205823-Liver, pubmed-meshheading:9205823-Middle Aged, pubmed-meshheading:9205823-Nephelometry and Turbidimetry, pubmed-meshheading:9205823-Phosphodiesterase Inhibitors, pubmed-meshheading:9205823-Regression Analysis, pubmed-meshheading:9205823-Theophylline, pubmed-meshheading:9205823-Tumor Necrosis Factor-alpha
pubmed:year
1997
pubmed:articleTitle
Endotoxin depresses hepatic cytochrome P450-mediated drug metabolism in women.
pubmed:affiliation
Department of Medicine-Division of Digestive Diseases, VA Hospital, Lexington, Kentucky 40511, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Controlled Clinical Trial