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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1997-8-25
|
| pubmed:abstractText |
103 patients who received a cyclosporine-treated primary cadaver kidney transplant (TX) at our center between 1985 and 1989, whose graft survived for more than 1 year and who accepted to undergo voiding cystography after TX were analyzed and grouped according to the highest grade (regardless to whether active or passive) of vesicourteral reflux (VUR): group 0, absent (n = 14); group 1-2, grade I or II (n = 62); group 3, grade III (n = 27). Patient follow-up ranged from 5 to 10 (median 7) years. Patient and graft survivals and prevalence of hypertension (defined as the persistent need of antihypertensive therapy), did not differ significantly between groups (Mantel-Cox test p: n.s. in all cases). GFR (Cockroft and Gault) and proteinuria were evaluated with ANOVA for repeated measures at 1, 2, 3, 4 and 5 years in the 96 patients (group 0: 13, group 1-2: 56, group 3: 27) whose grafts lasted for 5 years or more. Neither GFR values (p: n.s.) nor GFR behaviour over time (p: n.s.) differed between groups, although a progressive decline of GFR was noted in all groups (p < 0.002). Proteinuria neither showed any significant differences between groups in values (p: n.s.) or behaviour over time (p: n.s.), nor any trend in behaviour over time in all groups as a whole (p: n.s.). Finally, in the first 5 years after TX the 3 groups did not differ for number of urinary tract infections (UTIs) (mean value for all patients: 2.5, range 0-22, episodes/pt/5 years) (p: n.s.), or for number of UTIs with leukocyturia (mean 0.6, range 0-6, episodes/pt/5 years) (p: n.s.), or for number of febrile UTIs (mean 0.3, range 0-5, episodes/pt/5 years) (p: n.s.), or for number of UTIs with sepsis (mean 0.1, range 0-2, episodes/pt/5 years) (p: n.s.). The same results were obtained when, instead of episodes/ pt/5 years, percentages of patients without or with 1 or more of such episodes in the same period were considered. In conclusion, VUR does not seem to be hazardous for the transplanted kidney in the medium to long-term.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0301-0430
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
47
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
356-61
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9202864-Cadaver,
pubmed-meshheading:9202864-Case-Control Studies,
pubmed-meshheading:9202864-Cyclosporine,
pubmed-meshheading:9202864-Female,
pubmed-meshheading:9202864-Follow-Up Studies,
pubmed-meshheading:9202864-Glomerular Filtration Rate,
pubmed-meshheading:9202864-Graft Survival,
pubmed-meshheading:9202864-Humans,
pubmed-meshheading:9202864-Hypertension, Renal,
pubmed-meshheading:9202864-Immunosuppressive Agents,
pubmed-meshheading:9202864-Kidney Transplantation,
pubmed-meshheading:9202864-Male,
pubmed-meshheading:9202864-Postoperative Complications,
pubmed-meshheading:9202864-Prevalence,
pubmed-meshheading:9202864-Proteinuria,
pubmed-meshheading:9202864-Time Factors,
pubmed-meshheading:9202864-Urinary Tract Infections,
pubmed-meshheading:9202864-Vesico-Ureteral Reflux
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Vesicoureteral reflux after kidney transplantation: clinical significance in the medium to long-term.
|
| pubmed:affiliation |
Transplant Center, Treviso General Hospital, Italy.
|
| pubmed:publicationType |
Journal Article
|