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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1997-9-4
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pubmed:abstractText |
In order to understand the infection status of human herpesvirus 7 (HHV-7) in Taiwan and clarify the serological cross-reactivity between HHV-7 and HHV-6, a longitudinal study was carried out in 52 infants from whom 9 sera were available from birth to 6 years of age. All sera were tested for antibodies against HHV-6 and HHV-7 by indirect immunofluorescence assay. HHV-7 infection was not seen before 6 months of age and gradually emerged thereafter, reaching a cumulative rate of 28.8%, 67.3%, 73.1%, 78.8%, 82.7%, and 86.5% by the ages of 1, 2, 3, 4, 5 and 6 years, respectively. Primary HHV-6 infection induced a reactive HHV-7 antibody in 10/28 (35.7%) cases with a titre of no more than 10. Twenty-eight children (53.8%) were infected by HHV-6 earlier than HHV-7, while eight (15.4%) were infected by HHV-7 earlier than HHV-6. In summary, HHV-7 infected children later than HHV-6. A one-way cross-reaction of HHV-7 serology by HHV-6 was revealed and a titre of 20 is appropriate for defining HHV-7 infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0803-5253
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
86
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
604-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9202795-Adolescent,
pubmed-meshheading:9202795-Adult,
pubmed-meshheading:9202795-Child,
pubmed-meshheading:9202795-Child, Preschool,
pubmed-meshheading:9202795-Cross Reactions,
pubmed-meshheading:9202795-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:9202795-Herpesviridae Infections,
pubmed-meshheading:9202795-Herpesvirus 6, Human,
pubmed-meshheading:9202795-Herpesvirus 7, Human,
pubmed-meshheading:9202795-Humans,
pubmed-meshheading:9202795-Incidence,
pubmed-meshheading:9202795-Infant,
pubmed-meshheading:9202795-Longitudinal Studies,
pubmed-meshheading:9202795-Middle Aged,
pubmed-meshheading:9202795-Prevalence,
pubmed-meshheading:9202795-Risk Factors
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pubmed:year |
1997
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pubmed:articleTitle |
Primary infections of human herpesvirus-7 and herpesvirus-6: a comparative, longitudinal study up to 6 years of age.
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pubmed:affiliation |
Department of Pediatrics, College of Medicine, National Taiwan University, Taipei.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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