Linked Life Data

9200914

Source:http://linkedlifedata.com/resource/pubmed/id/9200914

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1997-9-5
pubmed:abstractText
In the immune system, it is most important to discriminate self from nonself and to acquire and maintain the unresponsiveness to self antigens, self-tolerance. Recently, the transgenic animals provides the evidence of the mechanism of self-tolerance induction. Self-tolerance is established mainly by elimination, clonal deletion, and functional inactivation, clonal energy, of the autoreactive T cells and B cells. Clonal deletion and clonal anergy are involved not only in the central tolerance, in thymus or bone marrow, but also in the peripheral tolerance. The failure of self-tolerance involves the induction of auto-immune disease.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0047-1852
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1331-6
pubmed:dateRevised
2011-7-27
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
[Clonal deletion and clonal anergy as the mechanism of self-tolerance induction].
pubmed:affiliation
Department of Internal Medicine, Utano National Hospital.
pubmed:publicationType
Journal Article, English Abstract, Review