Linked Life Data

9198970

Source:http://linkedlifedata.com/resource/pubmed/id/9198970

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-6-20
pubmed:abstractText
An enzyme-linked immunosorbent assay was established to detect autoantibodies in canine patients with hypothyroidism. Thyroglobulin, purified from thyroid glands of euthanized, healthy dogs, was used as antigen. Utilizing this test system, sera of 39 patients with hypothyroidism were screened for the presence of thyroglobulin specific autoantibodies. Positive titers were found in 38% of these dogs, whereas 18 out of 72 patients (25%) with other internal diseases showed a positive reaction. In addition 21 healthy dogs were tested for the presence of anti-thyroglobulin autoantibodies. Three dogs were found to be positive in the ELISA. Development of autoantibody titers was followed up in four cases over a period of one year. A steady decline of autoantibody titers was observed in three patients with hypothyroidism, whereas titers of one healthy dog remained high over this period.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0303-6286
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
170-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
[Canine hypothyroidism: detection of anti-thyroglobulin autoantibodies].
pubmed:affiliation
Institut für Physiologie, Physiologische Chemie und Tierernährung, Universität München.
pubmed:publicationType
Journal Article, English Abstract