9196205

Source:http://linkedlifedata.com/resource/pubmed/id/9196205

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0012655, umls-concept:C0039593, umls-concept:C0079488, umls-concept:C0080194, umls-concept:C0220825, umls-concept:C0441669, umls-concept:C1136254, umls-concept:C1275991
pubmed:issue	7
pubmed:dateCreated	1997-8-5
pubmed:abstractText	The Epsilometer test (E test; AB Biodisk, Solna, Sweden), a new quantitative technique for the determination of antimicrobial susceptibility, was compared to reference methods (agar dilution and broth microdilution) for the antimicrobial susceptibility testing of Helicobacter pylori. Seventy-one H. pylori strains isolated from patients with duodenal ulcers were tested against 20 antimicrobial agents. The E test and the agar dilution method were carried out on Mueller-Hinton agar; the broth microdilution method was performed with Mueller-Hinton broth. The E-test results showed excellent correlation with the agar dilution results, with 91.3 and 98.8% agreement within 1 and 2 log2 dilution steps, respectively, in a total of 1,350 tests. The correlation between the E-test results and the broth microdilution results was slightly higher, with 91.6 and 99.1% agreement within 1 and 2 log2 dilution steps, respectively, in a total of 1,317 tests. There were six major errors and two very major errors by the metronidazole E test compared to the results obtained by reference methods. Excellent agreement between E-test, agar dilution, and broth microdilution results was found for resistance to erythromycin (8%), clarithromycin (6%), and tetracycline (6%). Our results confirm that the E test is comparable to standardized methods for susceptibility testing. Therefore, the E test is a reliable and alternative method for testing H. pylori susceptibility to a wide range of antimicrobial agents in clinical practice.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-1401191, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-1590683, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-1774337, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-1912418, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-1968548, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-2037671, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-2055809, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-2642447, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-2935076, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-3276266, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-3402574, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-3429627, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-3517070, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-3700291, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-3777915, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-7814531, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-7820994, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-8263164, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-8444676, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-8537288, http://linkedlifedata.com/resource/pubmed/commentcorrection/9196205-9542964
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7505564
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	0095-1137
pubmed:author	pubmed-author:CarboneFF, pubmed-author:CatamoGG, pubmed-author:Di BonaventuraGG, pubmed-author:NeriMM, pubmed-author:PiccolominiRR
pubmed:issnType	Print
pubmed:volume	35
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1842-6
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:9196205-Anti-Bacterial Agents, pubmed-meshheading:9196205-Helicobacter pylori, pubmed-meshheading:9196205-Microbial Sensitivity Tests
pubmed:year	1997
pubmed:articleTitle	Comparative evaluation of the E test, agar dilution, and broth microdilution for testing susceptibilities of Helicobacter pylori strains to 20 antimicrobial agents.
pubmed:affiliation	Department of Biomedical Sciences, G. D'Annunzio University, Chieti, Italy.
pubmed:publicationType	Journal Article, Comparative Study, Research Support, Non-U.S. Gov't