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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1997-8-12
|
| pubmed:abstractText |
Rats with bilateral, electrophysiologically guided, ibotenic acid lesions of the gustatory thalamus (THLX) were tested for their ability to perform a variety of taste-guided behaviors. First, in daily 30-min sessions, the rats were given repeated 10-s access periods to a range of concentrations of sucrose, NaCl, or QHCl, plus water. Both the control and the THLX rats exhibited similar concentration-response functions, regardless of hydrational state. Next, on 3 trials, the rats were given 15 min access to 0.3 M l-alanine and then injected with LiCl (0.15 M, 1.33 ml/100 g body weight ip). All rats learned a taste aversion following 1 pairing with LiCl. Finally, on 3 separate occasions, the rats were injected with furosemide, and Na(+)-appetite was evaluated 24 hr later. All rats expressed an equivalent sodium appetite after the first furosemide injection, but only the control rats increased intake of 0.51 M NaCl with repeated sodium depletions. These observations reinforce prior data implying that an intact gustatory thalamus is not necessary for the expression of some taste-guided behaviors.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0735-7044
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
111
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
633-45
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:9189278-Animals,
pubmed-meshheading:9189278-Appetite,
pubmed-meshheading:9189278-Association Learning,
pubmed-meshheading:9189278-Avoidance Learning,
pubmed-meshheading:9189278-Brain Mapping,
pubmed-meshheading:9189278-Conditioning, Classical,
pubmed-meshheading:9189278-Dietary Sucrose,
pubmed-meshheading:9189278-Dose-Response Relationship, Drug,
pubmed-meshheading:9189278-Drinking,
pubmed-meshheading:9189278-Ibotenic Acid,
pubmed-meshheading:9189278-Lithium Chloride,
pubmed-meshheading:9189278-Male,
pubmed-meshheading:9189278-Motivation,
pubmed-meshheading:9189278-Rats,
pubmed-meshheading:9189278-Rats, Sprague-Dawley,
pubmed-meshheading:9189278-Sodium, Dietary,
pubmed-meshheading:9189278-Taste,
pubmed-meshheading:9189278-Thalamic Nuclei,
pubmed-meshheading:9189278-Water-Electrolyte Balance
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Gustatory functions, sodium appetite, and conditioned taste aversion survive excitotoxic lesions of the thalamic taste area.
|
| pubmed:affiliation |
Department of Biomedical Science, Universitá di Modena, Italy.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|