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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
7
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pubmed:dateCreated |
1997-8-13
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pubmed:databankReference |
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pubmed:abstractText |
CD4+ T cells are the main target for HIV. However, the highest HIV antigen concentration in infected subjects accumulates on the cell surface of follicular dendritic cells in the germinal centres of the lymphoid tissue. Germinal centres contain a T-helper cell subset which expresses CD57 molecules. Here we analysed virus replication and viral load in CD57+CD4+ germinal centre T cells and in the CD4+ T cells found mostly outside germinal centres (CD57-CD4+).
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0269-9370
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
849-57
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9189209-Antigens, CD57,
pubmed-meshheading:9189209-Base Sequence,
pubmed-meshheading:9189209-CD4-Positive T-Lymphocytes,
pubmed-meshheading:9189209-DNA, Viral,
pubmed-meshheading:9189209-Germinal Center,
pubmed-meshheading:9189209-HIV Infections,
pubmed-meshheading:9189209-HIV-1,
pubmed-meshheading:9189209-Humans,
pubmed-meshheading:9189209-Male,
pubmed-meshheading:9189209-Molecular Sequence Data,
pubmed-meshheading:9189209-Viral Load,
pubmed-meshheading:9189209-Virus Replication
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pubmed:year |
1997
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|
pubmed:articleTitle |
Germinal centre CD4+ T cells are an important site of HIV replication in vivo.
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pubmed:affiliation |
Department of Virology, University of Freiburg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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