Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-7-24
pubmed:abstractText
Since 01.04.90 the Dokumentationszentrum schwerer Hautreaktionen (dZh) in Freiburg has registered cases of severe skin reactions like erythema exsudativum multiforme majus, Stevens-Johnson syndrome and toxic epidermal necrolysis in Germany. With the largest study so far of histological slides from patients included in this registry we were able to show that the epidermal type of erythema multiforme described by Orfanos et al. is the histopathological correlated of these severe skin reactions. Except two biopsies all of the specimens taken from the registered patients showed histological characteristics of this type of erythema multiforme. These two cases are now reported. Clinical data and photographic documentation did not prove authentic erythema multiforme. The lesions of both patients were described as atypical macules and papules; mucosal sites were only locally involved. Biopsies taken from the patients had the characteristics of the dermal type of erythema multiforme (Orfanos et al.). We conclude that histomorphological characteristics of the dermal type, in addition to an atypical clinical course, favour another diagnosis, such as multiforme-like eruption.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0001-5555
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
The dermal type of erythema multiforme: a rare variant of Stevens-Johnson syndrome or cases of clinical misclassification?
pubmed:affiliation
Department of Dermatology, University of Freiburg, Germany.
pubmed:publicationType
Journal Article, Case Reports