Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1997-6-25
pubmed:abstractText
Cell-matrix and matrix-matrix interactions are of critical importance in regulating the development, maintenance and repair of articular cartilage. In this study, we examined the structural colocalisation of type VI collagen and fibronectin in isolated chondrons and long-term agarose cultured chondrocytes extracted from normal adult canine articular cartilage. Using double labelling immunohistochemistry in conjunction with dual channel confocal microscopy and digital image processing we demonstrate that type VI collagen and fibronectin are distributed in a similar staining pattern and are colocalised at the surface of cultured chondrocytes and isolated chondrons. The results suggest that type VI collagen and fibronectin may play a role in both cell-matrix adhesion and matrix-matrix cohesion in the pericellular microenvironment surrounding articular cartilage chondrocytes.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1323568, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1372838, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1397263, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1425570, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1487492, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1544908, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1556676, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1572410, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1689589, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1702626, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1717545, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1747115, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1756855, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1772294, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-1877856, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-2269670, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-2331486, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-2374594, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-2376132, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-2506410, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-2972252, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3028640, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3075620, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3182942, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3196336, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3219850, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3220794, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3357089, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3655835, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3681525, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3731745, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3938630, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-3997552, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-6354112, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-6363519, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-6723253, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-7678838, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-7897185, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-8276905, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-8305821, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-8416992, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-8511595, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-8587067, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-8742695, http://linkedlifedata.com/resource/pubmed/commentcorrection/9183676-8834440
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0021-8782
pubmed:author
pubmed:issnType
Print
pubmed:volume
190 ( Pt 4)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
523-32
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Structural colocalisation of type VI collagen and fibronectin in agarose cultured chondrocytes and isolated chondrons extracted from adult canine tibial cartilage.
pubmed:affiliation
Department of Anatomy, Faculty of Medicine and Health Sciences, University of Auckland, New Zealand. j.chang@auckland.ac.nz
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't