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pubmed-article:9182119pubmed:abstractTextThe efficacy of combination therapy with 5-flucytosine and an IgG1 monoclonal antibody to Cryptococcus neoformans capsular glucuronoxylomannan was studied in vitro with J774. 16 murine macrophage-like cells and in vivo in murine cryptococcal infection. The combination of 5-flucytosine and IgG1 was more effective in reducing the numbers of C. neoformans colony-forming units in vitro and in vivo than either agent alone.lld:pubmed
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pubmed-article:9182119pubmed:affiliationDepartment of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA.lld:pubmed
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