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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1997-6-10
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pubmed:abstractText |
The efficacy of combination therapy with 5-flucytosine and an IgG1 monoclonal antibody to Cryptococcus neoformans capsular glucuronoxylomannan was studied in vitro with J774. 16 murine macrophage-like cells and in vivo in murine cryptococcal infection. The combination of 5-flucytosine and IgG1 was more effective in reducing the numbers of C. neoformans colony-forming units in vitro and in vivo than either agent alone.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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|
pubmed:issn |
0305-7453
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pubmed:author |
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|
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
617-22
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9182119-Animals,
pubmed-meshheading:9182119-Antibodies, Monoclonal,
pubmed-meshheading:9182119-Antifungal Agents,
pubmed-meshheading:9182119-Cryptococcosis,
pubmed-meshheading:9182119-Cryptococcus neoformans,
pubmed-meshheading:9182119-Female,
pubmed-meshheading:9182119-Flucytosine,
pubmed-meshheading:9182119-Immunoglobulin G,
pubmed-meshheading:9182119-Macrophages,
pubmed-meshheading:9182119-Mice,
pubmed-meshheading:9182119-Mice, Inbred A,
pubmed-meshheading:9182119-Microbial Sensitivity Tests,
pubmed-meshheading:9182119-Phagocytosis,
pubmed-meshheading:9182119-Polysaccharides
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pubmed:year |
1996
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pubmed:articleTitle |
Combination of 5-flucytosine and capsule-binding monoclonal antibody in the treatment of murine Cryptococcus neoformans infections and in vitro.
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pubmed:affiliation |
Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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