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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1997-6-16
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pubmed:abstractText |
A laboratory-based study of diagnosed bacterial meningitis in the national paediatric hospital identified 852 cases of meningitis in the 8-year period 1987-1994. There were 587 culture-positive cases, of which Haemophilus influenzae (47%) and Streptococcus pneumoniae (32%) accounted for 80%. H. influenzae showed a remarkable increase of 700% during the study period. Most of the H. influenzae cases (90%) occurred in the 1st 2 years of life. Analysis of culture-negative specimens by antigen detection in the last 2 years also revealed the predominance of H. influenzae (71.4%) and S. pneumoniae (22.4%). Typing of H. influenzae isolates during this time showed that 98% of the strains were type b. This retrospective hospital-based study indicated a pronounced increase in the incidence of H. influenzae meningitis and strongly supports the need for large-scale Hib vaccination for young children. However, such nationwide intervention will probably need to be based on a prospective on a prospective and population-based surveillance of H. influenzae infections.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0272-4936
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9176570-Age Distribution,
pubmed-meshheading:9176570-Bangladesh,
pubmed-meshheading:9176570-Child,
pubmed-meshheading:9176570-Child, Preschool,
pubmed-meshheading:9176570-Humans,
pubmed-meshheading:9176570-Infant,
pubmed-meshheading:9176570-Infant, Newborn,
pubmed-meshheading:9176570-Meningitis, Bacterial,
pubmed-meshheading:9176570-Meningitis, Haemophilus,
pubmed-meshheading:9176570-Meningitis, Meningococcal,
pubmed-meshheading:9176570-Pneumococcal Infections,
pubmed-meshheading:9176570-Retrospective Studies
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pubmed:year |
1997
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pubmed:articleTitle |
The increasing burden of disease in Bangladeshi children due to Haemophilus influenzae type b meningitis.
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pubmed:affiliation |
Department of Microbiology, Bangladesh Institute of Child Health, Dhaka Shishu (Children's) Hospital, Dhaka, Bangladesh.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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