rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1997-7-1
|
pubmed:databankReference |
|
pubmed:abstractText |
Genes that encode mitochondrial homologues to the bacterial enzymes of fatty acid synthesis were found in various eukaryotic species. Inactivation of these genes leads to a disturbed mitochondrial respiration and an increase in mitochondrial lysophospholipids. We postulate that there is a mitochondrial biosynthetic system providing fatty acids for phospholipid repair. The mitochondrial acyl carrier protein may also play another role, supporting the formation of the respiratory NADH:ubiquinone oxidoreductase.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0014-5793
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
5
|
pubmed:volume |
407
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
249-52
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9175861-3-Oxoacyl-(Acyl-Carrier-Protein) Synthase,
pubmed-meshheading:9175861-Acyl Carrier Protein,
pubmed-meshheading:9175861-Animals,
pubmed-meshheading:9175861-Electron Transport Complex I,
pubmed-meshheading:9175861-Fatty Acids,
pubmed-meshheading:9175861-Humans,
pubmed-meshheading:9175861-Mitochondria,
pubmed-meshheading:9175861-Molecular Sequence Data,
pubmed-meshheading:9175861-NADH, NADPH Oxidoreductases,
pubmed-meshheading:9175861-NADH Dehydrogenase,
pubmed-meshheading:9175861-Oxygen Consumption,
pubmed-meshheading:9175861-Phospholipids,
pubmed-meshheading:9175861-Phylogeny,
pubmed-meshheading:9175861-Symbiosis
|
pubmed:year |
1997
|
pubmed:articleTitle |
Mitochondrial fatty acid synthesis: a relic of endosymbiontic origin and a specialized means for respiration.
|
pubmed:affiliation |
Institut für Biochemie, Heinrich-Heine-Universität Düsseldorf, Germany. Regina.Schneider@uni-duesseldorf.de
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Review
|