| pubmed-article:9174637 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9174637 | lifeskim:mentions | umls-concept:C0035366 | lld:lifeskim |
| pubmed-article:9174637 | lifeskim:mentions | umls-concept:C1257890 | lld:lifeskim |
| pubmed-article:9174637 | lifeskim:mentions | umls-concept:C0026769 | lld:lifeskim |
| pubmed-article:9174637 | lifeskim:mentions | umls-concept:C0035168 | lld:lifeskim |
| pubmed-article:9174637 | lifeskim:mentions | umls-concept:C0007585 | lld:lifeskim |
| pubmed-article:9174637 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:9174637 | lifeskim:mentions | umls-concept:C0282116 | lld:lifeskim |
| pubmed-article:9174637 | lifeskim:mentions | umls-concept:C2349943 | lld:lifeskim |
| pubmed-article:9174637 | pubmed:dateCreated | 1997-8-20 | lld:pubmed |
| pubmed-article:9174637 | pubmed:abstractText | Retroviral particles associated with reverse transcriptase (RT) activity in cell-cultures from MS patients have been reported by different groups. Cell-cultures have been used for the study and characterization of the corresponding retroviral genome which we have shown is related to ERV9 in the pol region. Previously unpublished details of a study with monocyte cultures are presented together with observations on leptomeningeal and choroid-plexus cultures. The generation of self-transformed cultures after inhibition of interferon, followed by the loss of retroviral expression and recurrent apoptosis, is analyzed. Retroviral particles with RT-activity are produced in monocyte cultures with an apparent correlation with MS disease activity. However, though leptomeningeal and choroid plexus cells from MS can be passaged for a limited period, their evolution in vitro is not compatible with stable retroviral expression. These culture limitations greatly hampered progress on the elucidation of the retroviral genome sequence. | lld:pubmed |
| pubmed-article:9174637 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9174637 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9174637 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9174637 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9174637 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9174637 | pubmed:issn | 0065-1427 | lld:pubmed |
| pubmed-article:9174637 | pubmed:author | pubmed-author:MichelMM | lld:pubmed |
| pubmed-article:9174637 | pubmed:author | pubmed-author:SeigneurinJ... | lld:pubmed |
| pubmed-article:9174637 | pubmed:author | pubmed-author:GarsonJ AJA | lld:pubmed |
| pubmed-article:9174637 | pubmed:author | pubmed-author:MallerDD | lld:pubmed |
| pubmed-article:9174637 | pubmed:author | pubmed-author:PerrotFF | lld:pubmed |
| pubmed-article:9174637 | pubmed:author | pubmed-author:MandrandBB | lld:pubmed |
| pubmed-article:9174637 | pubmed:author | pubmed-author:MarcecJJ | lld:pubmed |
| pubmed-article:9174637 | pubmed:author | pubmed-author:TujiKK | lld:pubmed |
| pubmed-article:9174637 | pubmed:author | pubmed-author:BesemeFF | lld:pubmed |
| pubmed-article:9174637 | pubmed:author | pubmed-author:BedinFF | lld:pubmed |
| pubmed-article:9174637 | pubmed:author | pubmed-author:FirouziRR | lld:pubmed |
| pubmed-article:9174637 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9174637 | pubmed:volume | 169 | lld:pubmed |
| pubmed-article:9174637 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9174637 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9174637 | pubmed:pagination | 22-31 | lld:pubmed |
| pubmed-article:9174637 | pubmed:dateRevised | 2007-7-23 | lld:pubmed |
| pubmed-article:9174637 | pubmed:meshHeading | pubmed-meshheading:9174637-... | lld:pubmed |
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| pubmed-article:9174637 | pubmed:meshHeading | pubmed-meshheading:9174637-... | lld:pubmed |
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| pubmed-article:9174637 | pubmed:meshHeading | pubmed-meshheading:9174637-... | lld:pubmed |
| pubmed-article:9174637 | pubmed:meshHeading | pubmed-meshheading:9174637-... | lld:pubmed |
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| pubmed-article:9174637 | pubmed:meshHeading | pubmed-meshheading:9174637-... | lld:pubmed |
| pubmed-article:9174637 | pubmed:meshHeading | pubmed-meshheading:9174637-... | lld:pubmed |
| pubmed-article:9174637 | pubmed:meshHeading | pubmed-meshheading:9174637-... | lld:pubmed |
| pubmed-article:9174637 | pubmed:meshHeading | pubmed-meshheading:9174637-... | lld:pubmed |
| pubmed-article:9174637 | pubmed:meshHeading | pubmed-meshheading:9174637-... | lld:pubmed |
| pubmed-article:9174637 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9174637 | pubmed:articleTitle | Cell cultures and associated retroviruses in multiple sclerosis. Collaborative Research Group on MS. | lld:pubmed |
| pubmed-article:9174637 | pubmed:affiliation | BioMérieux S.A., UMR 103 CNRS-bioMérieux, Lyon, France. | lld:pubmed |
| pubmed-article:9174637 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9174637 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9174637 | lld:pubmed |
